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  • Thank you so much to the SENS Research Foundation for sponsoring this video

  • I asked Triangle Bob to design what he thinks humans will look like in the year 2200.

  • He's been at it for like five hours now, so I'm just gonna see what he's done.

  • For the Love of Animator! What the heck is that?

  • Uh I..I mean Wow, Triangle Bob! They look great!

  • I see it says here that you've also added super mitochondria to make them live longer?

  • Okaywe'll have to explore this further! Cue the intro!

  • Hey there! Welcome to Life Noggin!

  • Turns out Triangle Bob was onto something with his mitochondrial Improvement DLC!

  • super small tweak can have a really huge impact on human evolution.

  • Yeah it's a pretty big dealbut to explain it further we need to travel inside the body.

  • Let's visit your body's power plantshall we?

  • Seat belts everyone! I've always wanted to say that.

  • Oh, wow! Here it is the city of mitotropolis!

  • If there's anything you humans remember from biology class, it's that mitochondria is the PowerHouse of the cell, but what does that really mean?

  • After you digest your food the byproducts make their way into your cellsand eventually into the mitochondria.

  • Here, they are broken down and made into a chemical called Adenosine Triphosphateor ATP.

  • This is what your cells use to store and transport the energy they need to function.

  • Uh oh! This isn't good! That process created waste products called free radicals!

  • These guys can damage important parts of your cells like mitochondrial DNA.

  • I mean, look at the mess they're making!

  • Normally, when we talk about DNA, we mean the DNA in your chromosomes, which are located in the cell's nucleus,

  • but mitochondria are really unique in that they have a small amount of their own DNAand I mean a really small amount.

  • There used to be a whole lot more actually, but as humans evolved the majority of them moved inside the nucleus, where it's a lot safer.

  • Scientists believe that the remaining ones are the most essential to the energy production process.

  • For instance, 13 of these genes create the chemicals needed to make the wonderful ATP.

  • We have to protect those guys

  • So here's the issue happening inside you, the beautiful flesh monster watching this video.

  • When mitochondrial DNA is damaged by free radicals, it can delete portions of the genetic code,

  • making it impossible to create these chemicals and make energy.

  • But the mutant mitochondria do keep making free radicals, which can cause oxidative stress,

  • leading to diseases like cancer, diabetesand heart disease, as well as aging. Humans disliked that.

  • Now, how do we even fix this?

  • While we can't prevent mitochondrial DNA from getting damaged,

  • scientists are finding ways to keep the mitochondria working properly by taking Evolution into their own hands!

  • Like the mitochondrial genes that already migrated to the nucleus on their own,

  • scientists are creating backup copies of the 13 essential genes in the mitochondrial DNA.

  • They're putting them in the nucleus as well, where they're protected.

  • Don't worry these backups will keep things running smoothly for longer.

  • One group of researchers has already begun working on this and created backup copies of two of the 13 genes, which they're testing in mice!

  • If this works out we could be seeing dramatic drops in cancer ratesage-related diseases,

  • and yeah, it'll slow down the aging process. Humans like that.

  • To learn more about this cool tech, go check out our sponsor over at the SENS Research Foundation.

  • They're doing amazing work in this fieldand they definitely should get your support!

  • So has there been anything you learned in school that you really want us to go into more detail about?

  • What would you love more information on?

  • Let me know in the comments section below!

  • Click here to watch this video about glowing bodies or click here to watch this video!

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  • And click the like button because it really helps us out!

  • You can also check out the team at lifespan that powers life Noggin down in the description!

  • As always, my name is Blocko. This has been Life Noggin. Don't forget to keep on thinking!

Thank you so much to the SENS Research Foundation for sponsoring this video

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