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  • Hi, this is Emily.

  • Animals of different species rarely get it on, and when they do, they rarely produce offspring.

  • But even rarer than the ligers, zonkeys, camas, and beefalo of the world are hybrid animals capable of making babies of their own.

  • In fact, the idea of a mule, the hybrid progeny of a female horse and a male donkey, having its own baby is so implausible that the ancient Romans used to employ the saying, when a mule falls, as a metaphor for the impossible.

  • The same way that Americans say, when pigs fly, Turkish people say, when fish climb trees, and Nigerians say, when the chicken has teeth.

  • Here's why.

  • In order to successfully reproduce, animals need to create viable sex cells.

  • Normal body cells have two copies of each chromosome, one from the animal's mom and one from dad, sort of like two full decks of cards.

  • And both decks can simply be duplicated and then split off to form a new cell.

  • But sex cells are different.

  • They're produced by taking each set of chromosomes, duplicating them, and then swapping a bunch of cards between decks before breaking them up to form four cells, each with just one complete deck of cards.

  • This card swap works when the decks in each set come from a mom and a dad of the same species, because they have all the same cards in the same order.

  • So genes for eye color get swapped with other genes for eye color, and stripe pattern genes get swapped with stripe pattern genes, giving rise to perfectly healthy sex cells.

  • But in the cells of hybrid animals, the decks aren't identical because they came from parents of different species.

  • So an eye color card might get swapped for a paw size card, or a bone-making gene for a kidney-making gene, producing two really weird decks that give rise to totally non-functional sex cells.

  • However, for reasons we really don't understand, it is sometimes possible for a hybrid animal to skip over the card swapping step and sort of just get rid of the dad's chromosomes to create new sex cells that contain only the mom's DNA.

  • We've actually only seen this happen in female mules.

  • There are a handful of documented cases in which mules have made babies from eggs containing only their mother's DNA.

  • Bizarrely, this means that each female mule's offspring was genetically also her half-sibling.

  • So while, as far as we know, pigs never fly, every once in a great while, a mule foals.

Hi, this is Emily.

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