Subtitles section Play video Print subtitles HARVARD RESEARCHERS BELIEVE THAT THEY CAN REVERSE DNA AGING. WELL AT LEAST THEY PROVEN THAT THEY CAN REVERSE DNA AGING IN MY SENSING THEY WILL BE TESTING THIS METHOD ON HUMANS AND IT IS A PRETTY BIG DEAL. THEY FOCUSED ON AN INTRIGUING COMPOUND WITH ANTIAGING PROPERTIES CALLED NAD+. IT'S BEEN KNOWN THAT YOUNGER MICE HAD MORE OF IT THAN OLDER MICE AND BACK IN 2013, THE RESEARCHERS FOUND THAT WHEN THEY BOOSTED THE NAD+ LEVELS IN OLDER MICE THEY LOOKED, BIOLOGICALLY, LIKE MUCH YOUNGER ANIMALS. BANANAS. THEY COULDN'T EVEN DIFFERENTIATE BETWEEN THE OLDER MICE IN THE YOUNGER MICE AFTER THEY STARTED GIVING THE OLDER MICE THIS COMPOUND. SINCLAIR, THAT'S ACTUALLY DOCTOR DAVID SINCLAIR FROM HARVARD, PUT DROPS OF NAD+ INTO THE WATER OF A GROUP OF MICE AND WITHIN A COUPLE OF HOURS, THEIR NAD+ LEVELS STARTED TO RISE THAT WITHIN THE FIRST WEEK, THE SCIENTISTS SAW OBVIOUS AGE REVERSAL IN MUSCLE AND IMPROVEMENTS IN DNA REPAIR. THAT'S IT, WEíRE DONE. THIS IS THE MOST IMPORTANT STORY THAT WE HAVE EVER COVERED. NOTHING ELSE MATTERS AT THE I AGREE WITH HER. THIS IS FREAKING PHENOMENAL AND I'M SUPER EXCITED THAT I WANT TO GET MY HANDS ON NAD+ IMMEDIATELY. I'M LOOKING AT CENK UYGUR'S NOTES AND THEYíRE HIGHLIGHTED THROUGH AND THROUGH. THE ENTIRE ARTICLE IS HIGHLIGHTED THROUGH AND THROUGH. YOU DIDN'T HAVE THIS LEVEL OF DETAIL - I DONíT KNOW IF YOU CAN SEE ALL THE HIGHLIGHTS. I GOT EXCITED I'M NOT MESSING AROUND WITH THAT. YOU HAVE TO STOP EATING NOW IF YOU WANT TO REMAIN HEALTHY REGARDLESS OF HOW YOUNG YOU BUT. NOT NECESSARILY MAN, AND THEN HAD PLEASANT EVERYTHING IS GOING TO BE OKAY TO LET ME QUOTE THE GOT THE DOCTOR AGAIN. WE CAN'T TELL THE DIFFERENCE BETWEEN TISSUES FROM AN OLD MOUSE THAT IS TWO YEARS OLD VERSUS A YOUNG MOUTH THAT IS 3 TO 4 MONTHS OLD. GOOD NIGHT, IRENE. OR NO GOOD NIGHTS. WEíRE GOING TO GET YOUNGER AND YOUNGER AND YOUNGER. HIT ME WITH NAD+. THE BEST PART IS YOU DON'T HAVE TO DO ANYTHING INVASIVE. YOU JUST HAVE TO CONSUME IT. BUT, IF THEY DID A TEST ON HUMANS WITH WHICH THEY PLAN ON DOING. THEY'RE GOING TO DO THE FIRST TEST ON 25 HUMANS TO SEE WHETHER OR NOT IT HAS THE SAME IMPACT ON THEM LIKE IT HAS ON THE MICE, BUT THE MICE JUST DRINK THAT SHIT UP. YOU KNOW? THEY DIDNíT HAVE TO DO ANYTHING CRAZY. NO IMPLANTS OR INJECTING ANYTHING. THEY INGESTED IT. WE WOULD JUST HAVE TO INGEST IT. IT IS THE MAGIC PILL. IT'S ALSO THE COMPOUND FOUND IN MICRO-DOSES AND BROCCOLI, AVOCADO, CUCUMBERS, THINGS THAT I EAT A LOT ACTUALLY, BUT WHAT I WAS GOING TO SAY THAT'S IT'S NOT WORKING ON YOU. WELL, DO YOU HEAR THAT? HERE'S WHAT I'M GOING TO SAY ñ IS NO ONE TERRIFIED BY THIS? THIS IS EVERY PLOT POINT TO EVERY ZOMBIE MOVIE EVER. THIS IS EXACTLY HOW ZOMBIE MOVIE START. THIS IS HOW YOU START. BLACK HELICOPTERS, ZOMBIES, I'M GLAD THAT THEY'RE DOING THE METRO BIOTECH IS IN BOSTON SO AT LEAST WILL BE CONTAINED IN THE AREA. WHAT MAKES YOU THINK IT WILL BE CONTAINED? REMEMBER DEATH BECOMES HER? 25 PEOPLE ARE GOING TO TURN INTO ZOMBIES. ARE GOING TO BE MISSING. BUT LUCKILY BECAUSE IT'S IN THE BOSTON AREA THEY WILL HANDLE IT QUICKLY BECAUSE EVERYONE KNOWS BOSTONIANS ARE VERY AGGRESSIVE ESPECIALLY AROUND FOOTBALL SEASON. I JUST GENERALIZED. WEíLL GET BACK TO THE STORY. THE WAY WE AGE IS DNA COPIES ITSELF AND SOMETIMES WHEN IT COPIES ITSELF IT'LL COPY A NOT SO PERFECT VERSION AND THAT IS WHAT KIND OF LEADS TO AGING. THAT IS AN OVERLY SIMPLISTIC WAY OF DESCRIBING AND ESSENTIALLY WHAT HAPPENS IS YOUR BODY NEEDS THESE DNA REPAIR COMPOUNDS IN ORDER TO REPAIR ITSELF IN A MORE EFFECTIVE WAY, AND A BETTER WAY, AND A MORE PERFECT WAY I GUESS. THAT IS WHAT PREVENTS AGING. THAT IS WHAT THIS IS, THEN ADD PLUS IS A DNA REPAIR COMPOUND. WITH HUMANS, THE REPAIR COMPOUND IS CONSUMMATE A LITTLE DIFFERENT THAT I CAN'T PRONOUNCE IT, BUT THE SHORT VERSION IS MNM. THE NATURALLY OCCURRING COMPOUND FOUND IN SMALL AMOUNTS IN FOODS LIKE BROCCOLI, CUCUMBER, AVOCADO, EDAMAME. I JUST WANT THE RECORD I'M A BIG FAN OF AVOCADO TOAST. I EAT A LOT OF IT. I FEEL VINDICATED ABOUT THAT. CAN I JUST SAY ONE THING. CAN Y'ALL CHECK TO SEE IF Y'ALL CAN CURE THE RATS FROM CANCER? WHY ARE WE SO PREOCCUPIED WITH YOUTH IN AMERICA? YOU CAN WALK AROUND WITH AN OLD SOUL. IT DOESN'T MATTER IF YOUR FACE DOESN'T MOVE. IT'S OKAY TO GET OLDER. WHY ARE WE SO PREOCCUPIED WITH NOT GETTING OLDER? IT'S OKAY. SO THAT'S A LARRY KING. IT'S SO MUCH PRESSURE ON WOMEN ALL THE TIME WITH THIS. STOP IT. WE CAN BE INVESTING THIS TIME INTO SOMETHING ELSE. IT'S NOT JUST ABOUT LOOKS, WHICH I WILL ADMIT, THAT'S THE PART OF IT THAT I CARE ABOUT THE MOST, BUT IT'S NOT JUST ABOUT THAT BECAUSE IT HELPS REBUILD HEALTHY TISSUE. ALSO, YOU BROUGHT UP CANCER AND I'M GLAD THAT YOU DID BECAUSE THIS COULD HAVE HUGE BENEFITS OF FOUR CANCER PATIENTS. APPARENTLY, SCIENTISTS HAVE HARNESS THIS TO TARGET CANCER CELLS, CANCER DRUG CALLED PAR PA INHIBITORS WHICH ARE PRESCRIBED FOR BREAST CANCER INTERFERE WITH PAR P'S ABILITY TO REPAIR DNA IN THE TUMOR WHICH ULTIMATELY LEADS TO THEIR DEMISE BUT NOW PEOPLE WHO TAKE THE DRUG RESPOND WELL TO WAY AND MANIPULATE THAT PLUS LEVELS MIGHT BE ONE WAY TO ENHANCE THE RESPONSE. IT COULD HELP CANCER PATIENTS AS WELL. LET ME TRY TO EXPLAIN, AGAIN ALL OF THIS IS A LITTLE OVERSIMPLISTIC. NOT PLUS, WHEN THEIR LEVELS ARE HIGHER THAN PAR P1 IS ACTIVATED AND CAN REPAIR THE DNA. IN THE CASE OF CANCER, YOU DON'T WANT TO REPAIR THE DNA OF THE CANCER CELLS SO THEY ACTUALLY LOWER THE PART AND THAT WINDS UP KILLING THE CANCER. IN THE CASE OF REVIVING YOUR YOUTH, YOU WANT THE PART TO BE HIGH ANYONE THAT PLUS LEVELS TO BE, BECAUSE WHEN THAT PLUS LEVELS ARE HIGH THAN PART ONE IS ACTIVATED AND THEN YOUR DNA HEELS AND YOU BECOME YOUNGER. THE BOTTOM LINE IS WE'RE NOT GOING TO DIE. I AM NOT PLAYING. LET ME GET REAL, I KNOW IT SOUNDS A LITTLE LIKE THE ZOMBIE THING THAT HOSPICE TALKING ABOUT, AND I AM NOT SAYING THEY IF YOU HAVE IN A CAR ACCIDENT, BEGIN A CAR ACCIDENT YOUR DEAD. OF COURSE. THIS DOESN'T MAGICALLY UNDEAD YOU. YOU ARE NICELY GOING TO HAVE ZOMBIES. THIS IS HOWEVER A TIME, AND EVERY SINGLE MOVIE LET ME TALK ABOUT HOW IT'S GOING TO BE REAL THOUGH. WE ARE ON THE EDGE OF SCIENTIFIC BREAKTHROUGHS THAT ARE GOING TO CHANGE THE ENTIRE WORLD. THE NUMBER ONE PROBLEM IS, I TALK ABOUT ALL THE TIME ON THE SHOW WHETHER IT'S POLITICS OR ANYTHING ELSE'S PEOPLE CANNOT SEE OUTSIDE OF THEIR OWN PERSPECTIVE. IN OUR LIFETIMES, WE'VE EVER SEEN IS THIS. YOU AGE, YOU GET OLDER, YOU CANíT MANIPULATE YOUR GENES, ETC. WE ARE ABOUT TO MANIPULATE THE GENES. WE ARE ABOUT TO MANIPULATE THE DNA. ITíS GOING TO AFFECT PEOPLE THAT ARE ALIVE. ITíS GOING TO AFFECT BABIES EVEN MORE BECAUSE WE CAN CHANGE THE DNA WITHIN THE WOMB. THAT IS NOW BORDERLINE EASY. I'VE BEEN TALKING ABOUT THIS FOR LONG TIME AND HE THINK I AM PLAYING OR EXAGGERATING. I AM NOT THAT THEY ARE GOING TO BE SUPER BABIES. THEY'RE GOING TO HAVE SLIGHTLY DIFFERENT GENES THAN US. THEY COULD BE STRONGER, IT'S POSSIBLE THEY COULD BE SMARTER. NOW YOU ARE TALKING ABOUT REAL SCIENCE-FICTION MOVIES BUT ISN'T FICTION ANYMORE. AND NOW, SCIENCE HAS ADVANCED SO MUCH THAT YOU MIGHT BE ABLE TO MANIPULATE GENES OF A PERSON WHO IS ALREADY ALIVE TO CURE THEM OF THINGS INCLUDING GROWING BACK LIMBS. WE CAN'T UNDERSTAND IT. ITíS A DIFFERENT PERSPECTIVE. WE THINK THAT CAN'T BE TRUE, RIGHT? SO WHEN WE LOOK AT THIS STUFF AND YOU THINK KNOW, YOU ARE EXAGGERATING. IT CAN'T REALLY MAKE YOU YOUNGER. IT ALREADY MADE THE MICE YOUNGER. IT ALREADY HAPPENED AND THEYíRE TESTING IN HUMANS. NOW 48 YEARS FROM NOW, NOT 88 YEARS FROM NOW, NOT A BRAVE NEW WORLD, TODAY. IT DOESN'T MEAN THAT IT IS GOING TO HAPPEN IN 18 MONTHS AND ALL OF A SUDDEN WE'RE ALL IMMORTAL. I ALSO WANT TO BRING DOWN YOUR EXPECTATIONS. OF COURSE THIS IS DANGEROUS AND IMPORTANT STUFF. THEY'RE GOING TO DO A TON OF TESTING BEFORE THEY ARE LIKE HEY, EVERYBODY NOT PAUSE FOR EVERYONE. YES WE ARE OVERSIMPLIFYING TO ALL THE THINGS ARE TRUE. BUT IF NOT FOR OUR GENERATION, DEFINITELY FOR KIDS GENERATION IS DEFINITELY GOING TO BE COMPLETELY DIFFERENT. ONCE YOU START MESSING AROUND WITH THE GENES, ALL BETS ARE OFF. FOR THE GOOD AND PROBABLY ALSO FOR THE BAD.
B1 US dna nad repair cancer younger compound Harvard Scientists REVERSE Aging In Mice. People Next... 86 9 Darren posted on 2017/04/01 More Share Save Report Video vocabulary