Subtitles section Play video Print subtitles >> Announcer: Live from Austin Texas, it's theCUBE, covering South by Southwest 2017, brought to you by Intel. Now, here's John Furrier. >> Welcome back everyone, we are live at the Intel AI Lounge, end of the day, day one at South by Southwest, I'm John Furrier, this is theCUBE, our flagship programming brought to the events and extract a signal from the noise. What a day it is here, it's the packed venue, AI Lounge, with Intel, it's the hottest spot in South by Southwest, of course, where our theme is AI for social good, and our next guest is Bryce Olson with Intel, and your title officially is, global marketing director health and live services, but you are an amazing story, cancer survivor, but a fighter, you took it to technology to stop your cancer, and also, a composer with your friend, called FACTS, Fighting Advanced Cancer Through Song, the stories. Welcome to theCUBE! >> Thank you, it's great to be here, this is awesome, this is amazing environment that we're in today. But yeah, you're right, when you look at data, genomics data, which is looking at your DNA, and running that out and being able to understand what could potentially be fueling disease, that's the biggest of big data. And when I was working at Intel, I was in a non-healthcare oriented group, and then all of a sudden, I got hit with cancer, like very aggressive, advanced cancer. And I went through the whole standard of care, and I went through that one-size-fits-all spin that wheel of treatments and hopefully you get something kind of thing, nothing-- >> General purpose, chemotherapy, whatever, blah blah blah. >> Nothing worked. And I came to the point where I was start to come to terms with the fact that I may not see my daughter get through elementary school. So, cancer's starting to grow again, I go back to work, at this point, I only want to work in healthcare, because, why would I want to do anything else? I want to try to-- >> John: But you have terminal cancer at this point. >> I have terminal cancer at this point, but I'm not sick yet. You know, I went through all the chemo and all that crap, but I'm not sick yet. So, I asked to get into Intel's healthcare group, because I want to try to help healthcare providers make this digital transformation. They let me in, and what I found out kind of blew my mind. I learned about this new space of genomics and precision medicine. >> Well, it turns out, hold on for a second, you were telling me the story before, but you skipped a step, it turns out Intel has a lot of work going on, so you come into Intel, you're like, they open up the kimono-- >> Open up the kimono, and I learn about this new era called, just basically genomics, so what is genomics? Genomics, essentially, is a way to look at disease differently. Why can't we go in and find out what's fueling disease deep in the DNA? Because every disease is diagnosable by DNA, we just have never had the technology, and the science, combining together to get to that answer before. Now we do. So I found out that Intel is working with all these genomic sequencing companies to increase the throughput so you can actually take something that costs $2 billion dollars back in 2003, and took 10 years to do, get it down to $1,000 and do it in a day, right? So now, it democratizes sequencing, so we can look at what's fueling disease and get the data. Then I learned about Intel working with all these major bioinformatics open stores and commercial providers, the Broad Institute at MIT, Harvard, largest genomic sequencing place on the planet, about how they take that data and then analyze it, get to what is really fueling disease. And then I learn about the cool things we're doing with customers, which I could talk about, like actual hospitals. >> Well, let's hold on for a second on that, your shirt says Sequence Me, but this is really key for the audience out there listening and watching, is that, literally 10 years ago the costs were astronomical, no one could afford it. Big grants, philanthropy-funded R&D centers, now, literally, you had your genome sequenced for thousands of dollars. >> Well, so, and this is what happened, right? I learned about all this stuff that Intel's up to, and I get kind of upset. I get kind of pissed off, right? Because nobody's giving this to me. Nobody's sequencing my cancer, right? So I go back to the cancer center that I was working with, this is January 2015, turns out they were getting ready, they were perfecting their lab diagnostic test on this, it was like a perfect storm, they were ready, I wanted it, they gave it to me, turns out my cancer grows along this particular mutated pathway that we had no idea. >> So the data was, so in your DNA sequence step one, step two is you go in massive compute power, which is available, and you go look at it, and it turns out there's a nuance to your cancer that's identifiable! >> Yeah, a needle in that haystack, right? The signal in the noise, if you will, right? So there's a specific molecular abnormality, and in my case, there was a pathway that was out of control, and the reason why I say it was out of control is, the pathway was mutated, but then there's this tumor suppressor gene that's supposed to stop cancer, he's gone! So it's like a freeway of traffic-- >> So he's checked out, and all of a sudden, this is going wild, but this is cancer for everyone has their own version of this. >> Yes they do. >> So this is now a new opportunity. >> Yes! Now we understand what's fueling my unique cancer. We took data, we took technology and science, and we got to the point where we understand what's fueling my cancer. With that data, I find a clinical trial testing a new inhibitor of that pathway. >> So I just got to stop and just pause, because it's very emotional, and first of all, man, yours is an inspiration to me and everyone watching. I'm looking at some sign this year at the Intel AI booth, and it says, "Your amazing starts with Intel," this is truly an amazing story. >> Yeah, thank you. >> It's really beyond amazing, it's life saving! >> And that's what happened to me. >> This is now at the beginning, so take me through, in your mind, where is the progress bar on this, in the AI evolution, or when I say AI, I mean like machine learning, compute, end-to-end technology innovation. It's available, obviously, when is it going to be mainstream? >> Yeah, so, we're at a point right now where we can go in, if you have advanced cancer, we're at a point now where we can sequence that person's cancer and find out what's driving it, we can do that. But where it's going to get problematic is, look at my case. The mutated pathway hypersegmented by cancer, right, so prostate cancer, a common cancer, now became a rare cancer, because we hypersegmented it by DNA, and I went after a treatment that was targeted, so when my cancer starts to grow again, now I'm a rare cancer. So how are going to find people that are just like me out there in the world? >> So your point about rare being, there's no comparable data to look at benchmarking, so that's the challenge. >> Yeah, no given hospital will ever have enough data in this new molecular genomics-guided medicine world to solve my problem, because the doctors are going to want to look, and they're going to say, "Who out there looks just like Bryce "from a DNA perspective, uniquely? "What treatments were given to people like that, "and what were the outcomes?" The only way we're going to solve that is as all these centers and hospitals start amassing data, it has to work together, it has to collaborate in a way that preserves patient privacy, and also protects individual IP. >> Okay, so Bryce, let me ask you a question, if you could put a bumper sticker or a soundbite around what AI means to this evolution innovation around fighting cancer and using data and technology, what is the impact of AI to this? >> So, where I'm kind of going with this analogy is that without artificial intelligence to sift through my data, and all the other millions of potential cancer patients to start getting DNA data, humans can't do it, it's impossible, humans will not have the mental ability to sift through reams and reams of DNA data that exists for every patient out there to look at treatments and outcomes and synthesize it, we can't do it. The only way someone like me will survive into the long term will be through artificial intelligence. Without it, I will extend my life, but I won't turn cancer into a manageable disease without AI. >> So the AI will extend your life. >> Because AI is going to solve the problems that humans can't. When you have the biggest of big data-- >> Love that soundbite, love that, say that again! AI solves the problems that-- >> AI is going to solve the problems that humans can't, they simply, humans don't have the capability to look at the entire genome, and all this other genomic, molecular, proteomic, all this other data, we can't make sense of it! >> Alright, so let me throw something out at you, 'cause I agree 100%, but also, there's a humanization factor, 'cause now algorithms are also biased by humans, so what's your thoughts, given your experience, the role of the human race, actual human beings, that have a pulse, not robots or algorithms? >> Yeah, so let me give you a real practical example. So, the way that we fought my cancer was through a targeted therapy. Molecular abnormality, targeted drug. The other way that people are fighting cancer is through immunotherapy. Wake up the immune system to fight it. Guess what? Right now, there are 800 combination therapies going on with immunotherapy to try to stop people's cancer. How the heck are we going to know what is the right combination for each person out there? Unless we have like an algorithm marketplace where people are creating these, and taking in predictive biomarkers, prognostic biomarkers, looking at all the data, and then pushing a button to help an oncologist decide which of the 800 combos to use, we'll never get there. So-- >> That's awesome. So let me ask you a question, so for people watching that are younger, like my daughter, she's 16, my other daughter's a premed, she's a sophomore in college, they're like, school's like old, like, school's like linear, they get classes, but this younger generation are hungry for data, they're hungry, they want to, they're young, they're what people do, they disrupt, they're bomb throwers, they want to create value, and so their incentive to go after cancer, and the means are out there, cancer cells, we all have relatives who have died of cancer, it's a sucky situation. There's a motivated force out there of scientists, and young people. How do they get involved? How would you look at, based on your experience, and your experience, obviously, you got these songs here, but on a more practical level, what discovery, what navigation can someone take in their life to just get involved, not a catalog, not the courseware. >> I think, so there's a number of different things that can happen, if you look at the precision medicine landscape, and you start with a patient, patients don't understand this. "Genomic what? "Sequencing what?" They don't understand that there's a new way to fight cancer, so guess what's going to become a 20% per year growth rate job in the next 10 to 20 years? Genomics counselors. You don't have to be a doctor, but you have to be able to understand enough about biology-- >> And math. >> To be able to offload doctors, and have a discussion with patients to say, "Let me explain something to you. "There's a way to understand your disease, it's in DNA, "this is what it means," and then help them guide them into new clinical trials and other therapy that's got it by that, huge growth opportunity for kids. >> But also, it's compounded by the fact we just said earlier, where these become rare cases on paper, are also need to be aggregated into a database of some sort so you can understand the data, so there's also a data science angle here. >> Absolutely, and it's not just cancer, by the way, I mean, little kids in the NICU, pediatric ailments. Have you ever know anybody who's got a kid with a very rare neurodevelopmental disorder, and the parents are on a diagnostic odyssey for 10 years, they can't figure out what it is? So they go from specialist to specialist, specialist, $100,000 dollars later, guess what, the answer's in the DNA. >> DNA sequencing, number one. >> DNA sequencing, number one, and then, once you start sequencing that, you got to make sense of all this data, so there's going to be tons of jobs, not only in biology, but in analytics, to take all this data and start finding-- >> Alright, we got a few minutes left, I want to get a plugin for your little album here, it's called FACTS, Fighting Against Cancer Through Song. >> So here's the story on that. So, when you go through something that could be terminal, it's really nice when you can have something productive to channel that energy. So for me, to be able to channel feelings of sadness and frustration, I started writing songs. Music was therapeutic for me. I took that, started collaborating with a bunch of musicians throughout Portland, including cancer survivors, and we said, why don't we use music as a way to reach people about a new message of how to fight cancer? So we created that, I have an organization that is raising awareness for a new way to fight cancer, and raising funds, to bring sequencing to more people. >> So the URL is factsmovement.com, so factsmovements.com, check it out. Okay, now, I'm so impressed with you, one, you are on a terminal track, you go back to work. >> But I don't look like I'm terminal! >> You look great, you look great. Now, you're at Intel, Intel's got technology, you harness it, now, you're on a mission now, your passion, it's obvious, the songs, now, what's going on in Intel, 'cause now you're out doing the Intel thing, gives us the Intel update. >> I can talk to you about this precision medicine, it's personalizing diagnostic and treatment plan, which I've already done, I could talk to you about other things that we're doing to help hospitals transform. Predictive clinical analytics, let's look at something like rapid response teamed events. Have you ever been in the hospital and heard the alarms go off? That's usually somebody having a heart attack unexpected. Data is out there, if you look at all the data about people that have had rapid response teams events, we can create predictive signals to actually predict that an hour before it would happen! So predictive clinical analytics, and enabling hospitals to look at populations as a whole to treat them better in this new value-based care, is a technology-driven thing, so we're working on that as well. Yeah. >> Well Bryce, thanks for coming on to theCUBE, we appreciate it, really inspirational, great to meet you in person, and I'm looking forward to following up with you when you get back to Portland, we'll get our gang in Palo Alto to get you on the horn Skype in, and keep in touch, really inspirational, but more importantly, this is very relevant, and the technology's now surfacing to change, not only people's lives in the sense of saving them, but other great things. >> And I'm so proud to be able to work for a company that is using its brand and its technology to basically change people's lives, it's amazing. >> Bryce Olson, my hero here at South by Southwest, amazing story, really, really, you can choose to be a victim or you can choose to go after it, so excited to have met you, it's theCUBE, breaking it all down here at South by Southwest at Intel's AI Lounge, it's hopping, music tonight, music tomorrow night, CUBE tomorrow, panels, AI changing the future powered by Intel, #IntelAI, I'm John Furrier, you're watching theCUBE, thanks for watching, we'll see you tomorrow.
B1 US cancer data ai sequencing dna fueling Bryce Olsen, Intel - SXSW 2017 - #IntelAI - #theCUBE 46 7 alex posted on 2017/04/10 More Share Save Report Video vocabulary