Before a doctorcanprescribe a drugortreatment, ithastobetestedinclinicaltrialstoverifyit's botheffectiveandsafeforpeopletouse.
So, justwhatis a clinicaltrialyoumightask?
Well, usingvolunteersorparticipants, a clinicaltrialis a researchstudythat's meanttoevaluate a neworexistingmedical, surgical, orbehavioralintervention.
Theyletusseeif a specifictreatment, maybe a medicaldevicelike a pacemakeror a vaccinetopreventchickenpoxissafe, effective, andifithasanybadsideeffectswhichareallveryimportant!
Backin 1932, thisstudyinvolved 600 blackmen, 399 withsyphilis, and 201 withoutit, who, inexchangeforbeing a partofthestudy, weretoldtheywouldgetadequatetreatment.
Butthatdidn't happen.
Evenwhenpenicillinbecamethego-totreatmentin 1947, researchersdidn't offerittotheparticipantsorgivethem a chancetoquitthestudy, whichlastedforanother 25 years.
TopreventanotherstudylikeTuskegee, thegovernmentpassedtheNationalResearchActin 1974, whichaddedmanyrulesandregulationstoprotectparticipantsandensureeverystudymeets a hostofethicalstandardsbeforeit's approved.
Ifyouvolunteerfor a clinicaltrialtoday, restassured, there's a wholenetworkofInstitutionalReviewBoards, orIRBs, thatguaranteeyoursafetyandprotectionintheresearch.