If people do lack social interactions and interpersonal touch and bond, uh they may feel demotivated or depressed.

This is because people are social in nature so they need that sort of connection.

How can this be avoided?

People can definitely avoid social isolation if they plan well, First be confident, secondly, make plans to meet friends and family.

I make a point that I call my family and friends for a get together during the weekends.