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  • Hope, patience, ups and downs.

    希望、耐心、起伏。

  • For couples facing fertility issues, the road from let's do this to meeting a happy, healthy baby can be an emotional rollercoaster.

    對於面臨生育問題的夫婦來說,從 "讓我們開始吧 "到迎接一個健康快樂的寶寶,這中間的過程可能會像坐雲霄飛車一樣情緒激動。

  • Now, there's a test that improves the odds for parents-to-be going through in vitro fertilization treatment.

    現在,有一種檢測方法可以提高準父母接受體外受精治療的機率。

  • And it all starts with a little math.

    這一切都要從數學開始。

  • A healthy pregnancy begins with a healthy embryo.

    健康的懷孕始於健康的胚胎。

  • One egg has 23 chromosomes.

    一個卵子有 23 條染色體。

  • So does one sperm.

    一個精子也是如此。

  • A fertilized egg contains half of mom's DNA and half of dad's.

    受精卵含有一半媽媽的 DNA 和一半爸爸的 DNA。

  • One day after fertilization, a healthy embryo begins to form with 46 chromosomes.

    受精一天後,一個擁有 46 條染色體的健康胚胎開始形成。

  • Sometimes an embryo has too many or too few chromosomes, causing a miscarriage or leading to birth defects.

    有時胚胎的染色體過多或過少,會導致流產或出生缺陷。

  • This happens 40 to 50% of the time, in fact, in both older and younger couples.

    事實上,這種情況在老年夫婦和年輕夫婦中都會發生,佔 40% 到 50%。

  • In addition to those odds, couples going through IVF face other challenges.

    除了這些機率之外,接受試管嬰兒的夫婦還面臨著其他挑戰。

  • It can take multiple tries to get pregnant, at a high cost, financially, emotionally, and physically.

    懷孕可能需要多次嘗試,在經濟、情感和身體上都要付出高昂的代價。

  • And when doctors transfer multiple embryos to improve the chance of pregnancy, the probability of twins, triplets, or more increases.

    當醫生為提高懷孕機率而移植多個胚胎時,雙胞胎、三胞胎或更多的可能性就會增加。

  • That's why researchers developed Preimplantation Genetic Screening, or PGS, a highly specialized genetic test performed in collaboration with IVF clinics worldwide.

    是以,研究人員開發了植入前遺傳學篩查(PGS),這是一種與全球試管嬰兒診所合作進行的高度專業化的遺傳學檢測。

  • The benefits are significant.

    效益顯著。

  • PGS dramatically increases rates of implantation and live births.

    PGS 能顯著提高植入率和活產率。

  • The test may reduce time between IVF cycles, if a second cycle is needed.

    如果需要進行第二次試管嬰兒週期,該測試可縮短兩次試管嬰兒週期之間的間隔時間。

  • PGS lowers many risks.

    PGS 降低了許多風險。

  • The risk of miscarriage early in pregnancy, the risk of a live birth in which the baby has a chromosomal abnormality, such as Down syndrome, and the risk, and costs, associated with multiple pregnancies.

    懷孕早期流產的風險、活產嬰兒染色體異常(如唐氏綜合症)的風險以及多胎妊娠的風險和成本。

  • Here's how it works.

    具體操作如下

  • The fertilized egg divides into two cells, then four, then eight, and so on.

    受精卵分裂成兩個細胞,然後是四個,八個,以此類推。

  • By day five, there are over 100 more distinctive cells.

    到了第五天,又出現了 100 多個獨特的細胞。

  • One cluster of cells will become the fetus, another, the placenta.

    一簇細胞將成為胎兒,另一簇細胞將成為胎盤。

  • An embryologist uses a small tool, 1-22nd the diameter of a human hair, to remove a few cells from the cluster that will become the placenta.

    胚胎學家用一個直徑只有頭髮絲1-22分之一的小工具,從將成為胎盤的細胞團中取出幾個細胞。

  • That sample is overnighted to a Cooper Genomics lab for testing, while your embryo stays safe in the care of your clinic.

    樣本將連夜送往庫珀基因組學實驗室進行檢測,而您的胚胎則由您的診所安全保管。

  • In the lab, we do two things.

    在實驗室裡,我們要做兩件事。

  • First, we make millions of copies of the DNA in those cells, so we have plenty to examine.

    首先,我們在這些細胞中複製了數百萬個 DNA 副本,是以我們有很多東西可以研究。

  • Then, we count the chromosomes in each sample removed from each of your developing embryos.

    然後,我們會對從每個發育中的胚胎中取出的樣本中的染色體進行計數。

  • This information is relayed to your clinic, where you and your doctor can make a more informed decision about treatment, and can transfer a healthy embryo.

    這些資訊將轉達給您的診所,您和您的醫生可以在那裡做出更明智的治療決定,並移植健康的胚胎。

  • That means a dramatically better chance of starting a pregnancy, with lower risk of complications.

    這意味著開始懷孕的機會大大增加,併發症的風險也更低。

  • Plus, other healthy embryos can be safely frozen for your future use.

    此外,其他健康的胚胎也可以安全地冷凍起來,供您將來使用。

  • Our mission is to advance the field of reproductive genetics and empower families worldwide.

    我們的使命是推動生殖遺傳學領域的發展,增強全球家庭的能力。

  • Cooper Genomics has already done this for tens of thousands of patients.

    庫珀基因組研究公司已經為數萬名患者完成了這項工作。

  • If you're thinking of IVF, or have already started, ask your doctor whether PGS fits your care plan.

    如果您正在考慮試管嬰兒,或者已經開始試管嬰兒,請諮詢醫生 PGS 是否適合您的治療計劃。

Hope, patience, ups and downs.

希望、耐心、起伏。

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