Name: 化學生物學概論128.講座05.非共價相互作用，DNA。 (Introduction to Chemical Biology 128. Lecture 05. Non-Covalent Interactions, DNA.)
Uploaded: 2021-01-14T05:18:31.000Z
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進階形容詞比較級句型

Was that at least as good as Russell Crowe?

First a quick quote, "Chemistry is to biology,

To me this really grabs at the essence of chemical biology

They allow other reformers to interpret the works in new ways

to be creative about biology and invent new ways

It's sort of the underlying basis at the level of atoms

and to me in some way this really captures what we're

OK. So this week, where it's already week 3

OK, so it's week 3 so we're up to chapter 3 and we're going

Our knowledge of DNA was really set in place

These are the giants really in the field of structural biology

who determined structures of DNA in the 1950s.

This includes the great Rosalind Franklin whose very accurate

x-ray diffraction structures and her pictures

of the x-rays diffracting off the fibers of DNA set

in motion the determination of the structure.

She was working with Maurice Wilkins and two physicists,

really one of their key insights was at the level of atoms

and bonds in the sense that they discovered interesting

tautomerization of the DNA bases that made it possible

to have what we now call Watson-Crick base pairing

Getting a little ahead of myself but that's where we're going

up non-covalent interactions then talking

and finally DNA reactivity of small molecules.

We have a lot to talk about, so bear with me.

Things are going to go not faster it's going

to be the same speed, but we're going to gloss

through a few topics that are less important and when we do,

this means then that you can focus your reading

and your study just on the level of detail

OK. Some announcements, in the textbook, read chapter 3.

Again, skim concepts not presented in lecture,

Chapter 3 problems, do all of the odd numbered and all

Many of you I know aspire to become physicians or scientists

or pharmacists or whatever it is that you aspire to do.

they require some evidence that you've gone beyond the ordinary

This is one that's run by my friend who is one

of the founders, it's called the Social Assistance Program

If you go to this website, there are opportunities to volunteer

to spend two weeks in Vietnam, in a rural part

of Vietnam administering medicine, you know.

You'll probably not be of course, you know,

drilling people's teeth and, you know, doing open heart surgery

to actually see those types of things happening

and that's really important if you aspire

It provides evidence that you're qualified, that you're committed

and that you're someone who is altruistic.

All of those things professional and graduate schools look

OK. I will help you get-- find those opportunities.

I'll bring them to your attention like this one.

And if there's something in particular that I can do

OK. Along those lines, our laboratory always has openings

It's competitive but you have a chance to participate

Undergraduates in our laboratory are doing actual science.

They're making discoveries and they're participating

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化學生物學概論128.講座05.非共價相互作用，DNA。 (Introduction to Chemical Biology 128. Lecture 05. Non-Covalent Interactions, DNA.)

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