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  • These days scientists know how you inherit

  • characteristics from your parents.

  • They are able to calculate probabilities

  • of having a specific trait

  • or getting a genetic disease

  • according to the information they have

  • from the parents and the family history.

  • But how is this possible?

  • To understand how traits pass

  • from one living being to its descendants,

  • we need to go back in time to the 19th century

  • and a man named Gregor Mendel.

  • Mendel was an Austrian monk and biologist

  • who loved to work with plants.

  • By breeding the pea plants

  • he was growing in the monastery's garden,

  • he discovered the principals that rule heredity.

  • In one of most classic examples,

  • Mendel combined a pure-bred, yellow-seeded plant

  • with a pure-bred, green-seeded plant,

  • and he got only yellow seeds.

  • He called the yellow-colored trait the dominant one

  • because it was expressed in all the new seeds.

  • Then he let the new yellow-seeded hybrid plants self-fertilize.

  • And in this second generation,

  • he got both yellow and green seeds,

  • which meant that the green trait had been hidden

  • by the dominant yellow.

  • He called this hidden trait the recessive trait.

  • From those results, Mendel inferred

  • that each trait depends on a pair of factors,

  • one of them coming from the mother

  • and the other from the father.

  • Now we know that these factors are called alleles

  • and represent the different variations of a gene.

  • Depending on which type of allele

  • Mendel found in each seed,

  • we can have what we call a homozygous pea,

  • where both alleles are identical,

  • and what we call a heterozygous pea,

  • when the two alleles are different.

  • This combination of alleles is known as genotype

  • and its result, being yellow or green,

  • is called phenotype.

  • To clearly visualize how alleles are distributed

  • among its descendants,

  • we can use a diagram called the Punnett Square.

  • You just place the different alleles on both axes

  • and then you figure out the possible combinations.

  • Let's look at Mendel's peas, for example.

  • Let's write the dominate yellow allele as an upper-case "Y"

  • and the recessive green allele as a lower-case "y".

  • The upper-case Y always overpowers his lower-case friend,

  • so the only time you get green babies

  • is if you have lower-case y's.

  • In Mendel's first generation,

  • the yellow, homozygous pea mom

  • will give each pea kid a yellow, dominant allele,

  • and the green, homozygous pea dad

  • will give a green, recessive allele.

  • So, all the pea kids will be yellow, heterozygous.

  • Then, in the second generation,

  • where the two heterozygous kids marry,

  • their babies could have any of the three possible genotypes,

  • showing the two possible phenotypes

  • in a three-to-one proportion.

  • But even peas have a lot of characteristics.

  • For example, besides for being yellow or green,

  • peas can be round or wrinkled,

  • so we could have all these possible combinations:

  • round yellow peas,

  • round green peas,

  • wrinkled yellow peas,

  • and wrinkled green peas.

  • To calculate the proportions of each genotype and phenotype,

  • you can use a Pennett Square too.

  • Of course, this will make it a little more complex.

  • And lots of things are more complicated than peas,

  • like, say, people.

  • These days scientists know a lot more

  • about genetics and heredity.

  • And, there are many other ways

  • in which some characteristics are inherited.

  • But, it all started with Mendel and his peas.

These days scientists know how you inherit

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【TED-Ed】 How Mendel's pea plants helped us understand genetics - Hortensia Jiménez Díaz

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    VoiceTube posted on 2013/04/15
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