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  • Well, it's great to be here.

  • We've heard a lot about the promise of technology, and the peril.

  • I've been quite interested in both.

  • If we could convert 0.03 percent

  • of the sunlight that falls on the earth into energy,

  • we could meet all of our projected needs for 2030.

  • We can't do that today because solar panels are heavy,

  • expensive and very inefficient.

  • There are nano-engineered designs,

  • which at least have been analyzed theoretically,

  • that show the potential to be very lightweight,

  • very inexpensive, very efficient,

  • and we'd be able to actually provide all of our energy needs in this renewable way.

  • Nano-engineered fuel cells

  • could provide the energy where it's needed.

  • That's a key trend, which is decentralization,

  • moving from centralized nuclear power plants and

  • liquid natural gas tankers

  • to decentralized resources that are environmentally more friendly,

  • a lot more efficient

  • and capable and safe from disruption.

  • Bono spoke very eloquently,

  • that we have the tools, for the first time,

  • to address age-old problems of disease and poverty.

  • Most regions of the world are moving in that direction.

  • In 1990, in East Asia and the Pacific region,

  • there were 500 million people living in poverty --

  • that number now is under 200 million.

  • The World Bank projects by 2011, it will be under 20 million,

  • which is a reduction of 95 percent.

  • I did enjoy Bono's comment

  • linking Haight-Ashbury to Silicon Valley.

  • Being from the Massachusetts high-tech community myself,

  • I'd point out that we were hippies also in the 1960s,

  • although we hung around Harvard Square.

  • But we do have the potential to overcome disease and poverty,

  • and I'm going to talk about those issues, if we have the will.

  • Kevin Kelly talked about the acceleration of technology.

  • That's been a strong interest of mine,

  • and a theme that I've developed for some 30 years.

  • I realized that my technologies had to make sense when I finished a project.

  • That invariably, the world was a different place

  • when I would introduce a technology.

  • And, I noticed that most inventions fail,

  • not because the R&D department can't get it to work --

  • if you look at most business plans, they will actually succeed

  • if given the opportunity to build what they say they're going to build --

  • and 90 percent of those projects or more will fail, because the timing is wrong --

  • not all the enabling factors will be in place when they're needed.

  • So I began to be an ardent student of technology trends,

  • and track where technology would be at different points in time,

  • and began to build the mathematical models of that.

  • It's kind of taken on a life of its own.

  • I've got a group of 10 people that work with me to gather data

  • on key measures of technology in many different areas, and we build models.

  • And you'll hear people say, well, we can't predict the future.

  • And if you ask me,

  • will the price of Google be higher or lower than it is today three years from now,

  • that's very hard to say.

  • Will WiMax CDMA G3

  • be the wireless standard three years from now? That's hard to say.

  • But if you ask me, what will it cost

  • for one MIPS of computing in 2010,

  • or the cost to sequence a base pair of DNA in 2012,

  • or the cost of sending a megabyte of data wirelessly in 2014,

  • it turns out that those are very predictable.

  • There are remarkably smooth exponential curves

  • that govern price performance, capacity, bandwidth.

  • And I'm going to show you a small sample of this,

  • but there's really a theoretical reason

  • why technology develops in an exponential fashion.

  • And a lot of people, when they think about the future, think about it linearly.

  • They think they're going to continue

  • to develop a problem

  • or address a problem using today's tools,

  • at today's pace of progress,

  • and fail to take into consideration this exponential growth.

  • The Genome Project was a controversial project in 1990.

  • We had our best Ph.D. students,

  • our most advanced equipment around the world,

  • we got 1/10,000th of the project done,

  • so how're we going to get this done in 15 years?

  • And 10 years into the project,

  • the skeptics were still going strong -- says, "You're two-thirds through this project,

  • and you've managed to only sequence

  • a very tiny percentage of the whole genome."

  • But it's the nature of exponential growth

  • that once it reaches the knee of the curve, it explodes.

  • Most of the project was done in the last

  • few years of the project.

  • It took us 15 years to sequence HIV --

  • we sequenced SARS in 31 days.

  • So we are gaining the potential to overcome these problems.

  • I'm going to show you just a few examples

  • of how pervasive this phenomena is.

  • The actual paradigm-shift rate, the rate of adopting new ideas,

  • is doubling every decade, according to our models.

  • These are all logarithmic graphs,

  • so as you go up the levels it represents, generally multiplying by factor of 10 or 100.

  • It took us half a century to adopt the telephone,

  • the first virtual-reality technology.

  • Cell phones were adopted in about eight years.

  • If you put different communication technologies

  • on this logarithmic graph,

  • television, radio, telephone

  • were adopted in decades.

  • Recent technologies -- like the PC, the web, cell phones --

  • were under a decade.

  • Now this is an interesting chart,

  • and this really gets at the fundamental reason why

  • an evolutionary process -- and both biology and technology are evolutionary processes --

  • accelerate.

  • They work through interaction -- they create a capability,

  • and then it uses that capability to bring on the next stage.

  • So the first step in biological evolution,

  • the evolution of DNA -- actually it was RNA came first --

  • took billions of years,

  • but then evolution used that information-processing backbone

  • to bring on the next stage.

  • So the Cambrian Explosion, when all the body plans of the animals were evolved,

  • took only 10 million years. It was 200 times faster.

  • And then evolution used those body plans

  • to evolve higher cognitive functions,

  • and biological evolution kept accelerating.

  • It's an inherent nature of an evolutionary process.

  • So Homo sapiens, the first technology-creating species,

  • the species that combined a cognitive function

  • with an opposable appendage --

  • and by the way, chimpanzees don't really have a very good opposable thumb --

  • so we could actually manipulate our environment with a power grip

  • and fine motor coordination,

  • and use our mental models to actually change the world

  • and bring on technology.

  • But anyway, the evolution of our species took hundreds of thousands of years,

  • and then working through interaction,

  • evolution used, essentially,

  • the technology-creating species to bring on the next stage,

  • which were the first steps in technological evolution.

  • And the first step took tens of thousands of years --

  • stone tools, fire, the wheel -- kept accelerating.

  • We always used then the latest generation of technology

  • to create the next generation.

  • Printing press took a century to be adopted;

  • the first computers were designed pen-on-paper -- now we use computers.

  • And we've had a continual acceleration of this process.

  • Now by the way, if you look at this on a linear graph, it looks like everything has just happened,

  • but some observer says, "Well, Kurzweil just put points on this graph

  • that fall on that straight line."

  • So, I took 15 different lists from key thinkers,

  • like the Encyclopedia Britannica, the Museum of Natural History, Carl Sagan's Cosmic Calendar

  • on the same -- and these people were not trying to make my point;

  • these were just lists in reference works,

  • and I think that's what they thought the key events were

  • in biological evolution and technological evolution.

  • And again, it forms the same straight line. You have a little bit of thickening in the line

  • because people do have disagreements, what the key points are,

  • there's differences of opinion when agriculture started,

  • or how long the Cambrian Explosion took.

  • But you see a very clear trend.

  • There's a basic, profound acceleration of this evolutionary process.

  • Information technologies double their capacity, price performance, bandwidth,

  • every year.

  • And that's a very profound explosion of exponential growth.

  • A personal experience, when I was at MIT --

  • computer taking up about the size of this room,

  • less powerful than the computer in your cell phone.

  • But Moore's Law, which is very often identified with this exponential growth,

  • is just one example of many, because it's basically

  • a property of the evolutionary process of technology.

  • I put 49 famous computers on this logarithmic graph --

  • by the way, a straight line on a logarithmic graph is exponential growth --

  • that's another exponential.

  • It took us three years to double our price performance of computing in 1900,

  • two years in the middle; we're now doubling it every one year.

  • And that's exponential growth through five different paradigms.

  • Moore's Law was just the last part of that,

  • where we were shrinking transistors on an integrated circuit,

  • but we had electro-mechanical calculators,

  • relay-based computers that cracked the German Enigma Code,

  • vacuum tubes in the 1950s predicted the election of Eisenhower,

  • discreet transistors used in the first space flights

  • and then Moore's Law.

  • Every time one paradigm ran out of steam,

  • another paradigm came out of left field to continue the exponential growth.

  • They were shrinking vacuum tubes, making them smaller and smaller.

  • That hit a wall. They couldn't shrink them and keep the vacuum.

  • Whole different paradigm -- transistors came out of the woodwork.

  • In fact, when we see the end of the line for a particular paradigm,

  • it creates research pressure to create the next paradigm.

  • And because we've been predicting the end of Moore's Law

  • for quite a long time -- the first prediction said 2002, until now it says 2022.

  • But by the teen years,

  • the features of transistors will be a few atoms in width,

  • and we won't be able to shrink them any more.

  • That'll be the end of Moore's Law, but it won't be the end of

  • the exponential growth of computing, because chips are flat.

  • We live in a three-dimensional world; we might as well use the third dimension.

  • We will go into the third dimension

  • and there's been tremendous progress, just in the last few years,

  • of getting three-dimensional, self-organizing molecular circuits to work.

  • We'll have those ready well before Moore's Law runs out of steam.

  • Supercomputers -- same thing.

  • Processor performance on Intel chips,

  • the average price of a transistor --

  • 1968, you could buy one transistor for a dollar.

  • You could buy 10 million in 2002.

  • It's pretty remarkable how smooth

  • an exponential process that is.

  • I mean, you'd think this is the result of some tabletop experiment,

  • but this is the result of worldwide chaotic behavior --

  • countries accusing each other of dumping products,

  • IPOs, bankruptcies, marketing programs.

  • You would think it would be a very erratic process,

  • and you have a very smooth

  • outcome of this chaotic process.

  • Just as we can't predict

  • what one molecule in a gas will do --

  • it's hopeless to predict a single molecule --

  • yet we can predict the properties of the whole gas,

  • using thermodynamics, very accurately.

  • It's the same thing here. We can't predict any particular project,

  • but the result of this whole worldwide,

  • chaotic, unpredictable activity of competition

  • and the evolutionary process of technology is very predictable.

  • And we can predict these trends far into the future.

  • Unlike Gertrude Stein's roses,

  • it's not the case that a transistor is a transistor.

  • As we make them smaller and less expensive,

  • the electrons have less distance to travel.

  • They're faster, so you've got exponential growth in the speed of transistors,

  • so the cost of a cycle of one transistor

  • has been coming down with a halving rate of 1.1 years.

  • You add other forms of innovation and processor design,

  • you get a doubling of price performance of computing every one year.

  • And that's basically deflation --

  • 50 percent deflation.

  • And it's not just computers. I mean, it's true of DNA sequencing;

  • it's true of brain scanning;

  • it's true of the World Wide Web. I mean, anything that we can quantify,

  • we have hundreds of different measurements

  • of different, information-related measurements --

  • capacity, adoption rates --

  • and they basically double every 12, 13, 15 months,

  • depending on what you're looking at.

  • In terms of price performance, that's a 40 to 50 percent deflation rate.

  • And economists have actually started worrying about that.

  • We had deflation during the Depression,

  • but that was collapse of the money supply,

  • collapse of consumer confidence, a completely different phenomena.

  • This is due to greater productivity,

  • but the economist says, "But there's no way you're going to be able to keep up with that.

  • If you have 50 percent deflation, people may increase their volume

  • 30, 40 percent, but they won't keep up with it."

  • But what we're actually seeing is that

  • we actually more than keep up with it.

  • We've had 28 percent per year compounded growth in dollars

  • in information technology over the last 50 years.

  • I mean, people didn't build iPods for 10,000 dollars 10 years ago.

  • As the price performance makes new applications feasible,

  • new applications come to the market.

  • And this is a very widespread phenomena.

  • Magnetic data storage --

  • that's not Moore's Law, it's shrinking magnetic spots,

  • different engineers, different companies, same exponential process.

  • A key revolution is that we're understanding our own biology

  • in these information terms.

  • We're understanding the software programs

  • that make our body run.

  • These were evolved in very different times --

  • we'd like to actually change those programs.

  • One little software program, called the fat insulin receptor gene,

  • basically says, "Hold onto every calorie,

  • because the next hunting season may not work out so well."

  • That was in the interests of the species tens of thousands of years ago.

  • We'd like to actually turn that program off.

  • They tried that in animals, and these mice ate ravenously

  • and remained slim and got the health benefits of being slim.

  • They didn't get diabetes; they didn't get heart disease;

  • they lived 20 percent longer; they got the health benefits of caloric restriction

  • without the restriction.

  • Four or five pharmaceutical companies have noticed this,

  • felt that would be

  • interesting drug for the human market,

  • and that's just one of the 30,000 genes

  • that affect our biochemistry.

  • We were evolved in an era where it wasn't in the interests of people

  • at the age of most people at this conference, like myself,

  • to live much longer, because we were using up the precious resources

  • which were better deployed towards the children

  • and those caring for them.

  • So, life -- long lifespans --

  • like, that is to say, much more than 30 --

  • weren't selected for,

  • but we are learning to actually manipulate

  • and change these software programs

  • through the biotechnology revolution.

  • For example, we can inhibit genes now with RNA interference.

  • There are exciting new forms of gene therapy

  • that overcome the problem of placing the genetic material

  • in the right place on the chromosome.

  • There's actually a -- for the first time now,

  • something going to human trials, that actually cures pulmonary hypertension --

  • a fatal disease -- using gene therapy.

  • So we'll have not just designer babies, but designer baby boomers.

  • And this technology is also accelerating.

  • It cost 10 dollars per base pair in 1990,

  • then a penny in 2000.

  • It's now under a 10th of a cent.

  • The amount of genetic data --

  • basically this shows that smooth exponential growth

  • doubled every year,

  • enabling the genome project to be completed.

  • Another major revolution: the communications revolution.

  • The price performance, bandwidth, capacity of communications measured many different ways;

  • wired, wireless is growing exponentially.

  • The Internet has been doubling in power and continues to,

  • measured many different ways.

  • This is based on the number of hosts.

  • Miniaturization -- we're shrinking the size of technology

  • at an exponential rate,

  • both wired and wireless.

  • These are some designs from Eric Drexler's book --

  • which we're now showing are feasible

  • with super-computing simulations,

  • where actually there are scientists building

  • molecule-scale robots.

  • One has one that actually walks with a surprisingly human-like gait,

  • that's built out of molecules.

  • There are little machines doing things in experimental bases.

  • The most exciting opportunity

  • is actually to go inside the human body

  • and perform therapeutic and diagnostic functions.

  • And this is less futuristic than it may sound.

  • These things have already been done in animals.

  • There's one nano-engineered device that cures type 1 diabetes. It's blood cell-sized.

  • They put tens of thousands of these

  • in the blood cell -- they tried this in rats --

  • it lets insulin out in a controlled fashion,

  • and actually cures type 1 diabetes.

  • What you're watching is a design

  • of a robotic red blood cell,

  • and it does bring up the issue that our biology

  • is actually very sub-optimal,

  • even though it's remarkable in its intricacy.

  • Once we understand its principles of operation,

  • and the pace with which we are reverse-engineering biology is accelerating,

  • we can actually design these things to be

  • thousands of times more capable.

  • An analysis of this respirocyte, designed by Rob Freitas,

  • indicates if you replace 10 percent of your red blood cells with these robotic versions,

  • you could do an Olympic sprint for 15 minutes without taking a breath.

  • You could sit at the bottom of your pool for four hours --

  • so, "Honey, I'm in the pool," will take on a whole new meaning.

  • It will be interesting to see what we do in our Olympic trials.

  • Presumably we'll ban them,

  • but then we'll have the specter of teenagers in their high schools gyms

  • routinely out-performing the Olympic athletes.

  • Freitas has a design for a robotic white blood cell.

  • These are 2020-circa scenarios,

  • but they're not as futuristic as it may sound.

  • There are four major conferences on building blood cell-sized devices;

  • there are many experiments in animals.

  • There's actually one going into human trial,

  • so this is feasible technology.

  • If we come back to our exponential growth of computing,

  • 1,000 dollars of computing is now somewhere between an insect and a mouse brain.

  • It will intersect human intelligence

  • in terms of capacity in the 2020s,

  • but that'll be the hardware side of the equation.

  • Where will we get the software?

  • Well, it turns out we can see inside the human brain,

  • and in fact not surprisingly,

  • the spatial and temporal resolution of brain scanning is doubling every year.

  • And with the new generation of scanning tools,

  • for the first time we can actually see

  • individual inter-neural fibers

  • and see them processing and signaling in real time --

  • but then the question is, OK, we can get this data now,

  • but can we understand it?

  • Doug Hofstadter wonders, well, maybe our intelligence

  • just isn't great enough to understand our intelligence,

  • and if we were smarter, well, then our brains would be that much more complicated,

  • and we'd never catch up to it.

  • It turns out that we can understand it.

  • This is a block diagram of

  • a model and simulation of the human auditory cortex

  • that actually works quite well --

  • in applying psychoacoustic tests, gets very similar results to human auditory perception.

  • There's another simulation of the cerebellum --

  • that's more than half the neurons in the brain --

  • again, works very similarly to human skill formation.

  • This is at an early stage, but you can show

  • with the exponential growth of the amount of information about the brain

  • and the exponential improvement

  • in the resolution of brain scanning,

  • we will succeed in reverse-engineering the human brain

  • by the 2020s.

  • We've already had very good models and simulation of about 15 regions

  • out of the several hundred.

  • All of this is driving

  • exponentially growing economic progress.

  • We've had productivity go from 30 dollars to 150 dollars per hour

  • of labor in the last 50 years.

  • E-commerce has been growing exponentially. It's now a trillion dollars.

  • You might wonder, well, wasn't there a boom and a bust?

  • That was strictly a capital-markets phenomena.

  • Wall Street noticed that this was a revolutionary technology, which it was,

  • but then six months later, when it hadn't revolutionized all business models,

  • they figured, well, that was wrong,

  • and then we had this bust.

  • All right, this is a technology

  • that we put together using some of the technologies we're involved in.

  • This will be a routine feature in a cell phone.

  • It would be able to translate from one language to another.

  • So let me just end with a couple of scenarios.

  • By 2010 computers will disappear.

  • They'll be so small, they'll be embedded in our clothing, in our environment.

  • Images will be written directly to our retina,

  • providing full-immersion virtual reality,

  • augmented real reality. We'll be interacting with virtual personalities.

  • But if we go to 2029, we really have the full maturity of these trends,

  • and you have to appreciate how many turns of the screw

  • in terms of generations of technology, which are getting faster and faster, we'll have at that point.

  • I mean, we will have two-to-the-25th-power

  • greater price performance, capacity and bandwidth

  • of these technologies, which is pretty phenomenal.

  • It'll be millions of times more powerful than it is today.

  • We'll have completed the reverse-engineering of the human brain,

  • 1,000 dollars of computing will be far more powerful

  • than the human brain in terms of basic raw capacity.

  • Computers will combine

  • the subtle pan-recognition powers

  • of human intelligence with ways in which machines are already superior,

  • in terms of doing analytic thinking,

  • remembering billions of facts accurately.

  • Machines can share their knowledge very quickly.

  • But it's not just an alien invasion of intelligent machines.

  • We are going to merge with our technology.

  • These nano-bots I mentioned

  • will first be used for medical and health applications:

  • cleaning up the environment, providing powerful fuel cells

  • and widely distributed decentralized solar panels and so on in the environment.

  • But they'll also go inside our brain,

  • interact with our biological neurons.

  • We've demonstrated the key principles of being able to do this.

  • So, for example,

  • full-immersion virtual reality from within the nervous system,

  • the nano-bots shut down the signals coming from your real senses,

  • replace them with the signals that your brain would be receiving

  • if you were in the virtual environment,

  • and then it'll feel like you're in that virtual environment.

  • You can go there with other people, have any kind of experience

  • with anyone involving all of the senses.

  • "Experience beamers," I call them, will put their whole flow of sensory experiences

  • in the neurological correlates of their emotions out on the Internet.

  • You can plug in and experience what it's like to be someone else.

  • But most importantly,

  • it'll be a tremendous expansion

  • of human intelligence through this direct merger with our technology,

  • which in some sense we're doing already.

  • We routinely do intellectual feats

  • that would be impossible without our technology.

  • Human life expectancy is expanding. It was 37 in 1800,

  • and with this sort of biotechnology, nano-technology revolutions,

  • this will move up very rapidly

  • in the years ahead.

  • My main message is that progress in technology

  • is exponential, not linear.

  • Many -- even scientists -- assume a linear model,

  • so they'll say, "Oh, it'll be hundreds of years

  • before we have self-replicating nano-technology assembly

  • or artificial intelligence."

  • If you really look at the power of exponential growth,

  • you'll see that these things are pretty soon at hand.

  • And information technology is increasingly encompassing

  • all of our lives, from our music to our manufacturing

  • to our biology to our energy to materials.

  • We'll be able to manufacture almost anything we need in the 2020s,

  • from information, in very inexpensive raw materials,

  • using nano-technology.

  • These are very powerful technologies.

  • They both empower our promise and our peril.

  • So we have to have the will to apply them to the right problems.

  • Thank you very much.

  • (Applause)

Well, it's great to be here.

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