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  • For most people when they drink alcohol, it can make them feel more confident and comfortable

  • But for me, drinking makes me feel less confident and uncomfortable.

  • That's because thanks to my DNA, alcohol makes my skin turn red

  • It's called the Asian Flush.

  • And it affects about 36% of North East Asians with higher rates among Asian Americans.

  • I guess we should probably show you what it looks like.

  • For Science!

  • If I know that I'm gonna need to take pictures that I'll drink less until these pictures are over and then I'll go back to normal pace.

  • People tend to assume that a red face means that we're drunk, but that's a myth.

  • These are completely separate processes.

  • Facial flushing whether from embarrassment, or exercise, or alcohol,

  • it happens when the blood vessels under the surface of the skin dilate.

  • And in the case of Asian flush, this is part of an immune response.

  • The body is detecting a threat.

  • The threat isn't the alcohol itself, but a substance that our livers produce while breaking down alcohol.

  • For me at least, the warmth starts in my chest and then it moves its way up.

  • My cheeks are warm, my ears are warm.

  • It's weird. It's like my eyes are almost puffy.

  • Ahh, I do feel like they got puffy.

  • When people drink ethanol, that's the chemical name for booze, the liver gets rid of it using two main enzymes.

  • The first reacts with the ethanol molecule to produce a substance called acetaldehyde.

  • And the second quickly turns acetaldehyde into acetate, which is similar to vinegar and easy for the body to eliminate.

  • It's that second enzyme that really screws things up for people with Asian flush.

  • If you look inside our DNA, you'll find that the gene providing the instructions for that enzyme was tweaked at some point in our history.

  • And that gene mutation produces an inactive enzyme.

  • So when we drink, our bodies accumulate acetaldehyde at a level about 6 times higher than normal people

  • If acetaldehyde sounds familiar that maybe because it's similar to formaldehyde.

  • It's toxic.

  • That's why it triggers the immune responds.

  • And the red face is really the least of it.

  • After having that one beer, I didn't feel tipsy at all, but my heart rate doubled.

  • My eyes were bloodshot, and within half hour, I had a headache.

  • Even worse, acetaldehyde can cause cancer.

  • It's a problem because people can actually develop a tolerance to Asian flush, and that allows them to drink pretty heavily.

  • Studies have shown that heavy drinking raises the risk of esophageal cancer for everyone, but especially for people with Asian flush.

  • So it's potentially problematic that alcohol consumption in Asia has been increasing, especially in China.

  • So if you have an Asian flush, be careful.

  • Your body is freaking out for a reason.

  • And if you don't flush, well, just don't expect us to keep up with you.

  • And also...

  • You don't have to bring it up every time...like, yes I know that I turn red.

  • I know this, thanks, awesome.

For most people when they drink alcohol, it can make them feel more confident and comfortable

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