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Post-Mortems are tightly controlled and access to them is strictly limited to protect the privacy and dignity of the deceased
Filming is not usually allowed
But for this post-mortem we have been allowed in to help understand a problem that costs the nation billions and ruin so many lives
obesity
Carla Valentine and Dr.. Mike Osborne are the specialist team responsible for carrying out the postmortem?
Carla is an anatomical Pathology technologist and technical curator of the Pathology Museum at London's, Queen Mary University
For this postmortem. I'll be carrying out the evisceration which means we're moving all of the organs
Being part of a filmed postmortem is a very unique opportunity
Death terrifies some people, but what it also does is it eventually gives you a real sense of the fragility of life?
The topic of obesity is a huge problem, and it's something that I get to see quite a lot
But it's not something that I get study in depth
Mind is a consultant pathologist and fellow of the Royal college of Pathologist
He's been working with death and disease for over 20 years
Obesity is very much there. It's seen but I think it's very very poorly understood
it seemed that making this film would be a way of exploring that and
Allowing a broader public to learn about the problems that are associated with obesity
Caller and Mike have performed thousands of Post-Mortems, but always behind closed doors
today
we will witness what really happens in an autopsy and
Discover what the body of our donor can tell us about the creeping effects of obesity over time
We don't know this woman's name, but we do know a few details about her
to within our only
65 foot size
almost 17 stone
And just like a quarter of people in the uk clinically obese
But where did she come from and how did she end up here on a post mortem table in London?
and
Finally she arrived in London her body remains in a pool chamber for ten days to allow it to fall completely
Before it was brought to the post-mortem table
The first stage of every Post-Mortem before any cuts is made to the flesh is an external examination of the body
the donors Id number is confirmed against her medical records which details the cause of her death heart disease and
That you'd only had minor surgery and drank minimal alcohol
But what will her body go on to reveal about the way that she died?
This lady's died of heart disease. Which is one of the things that is associated with obesity and interestingly
Already in this lady. We've got signs of heart failure because if I press here particularly on this side
You can say I'm very demanding there, and that's because you've got too much fluid and that's the side effect of heart failure
The other obvious external damage to our donor are the blisters on her skin?
They are one of the earliest signs of her body decomposing after death, and they're particularly noticeable on larger bodies
But they're not what Mike and Carla are focusing on
The most important thing about this lady
Is that the obesity that she's got is centered on her abdomen, so this lady's carrying a lot of weight around her tummy
That's associated with more of the complications than if somebody weighs the same
But they carry their weight around the bottom and around the thighs so that's less
Associated with complications. That's more associated with complications
so we can see the
distribution of the fats from the external exam
But once we actually get inside
We'll see more of how that's affected the inside of her body and her internal organs as well
When we open this lady there may be other
Findings that are less easy to diagnose before somebody has died that won't have killed her
but are
Examples of problems that can get worse and leads to illness and death in other people so we may find some of those we may
not
To uncover if there are deadly medical truths lying, beneath the skin calamus first cut open the body
The incision is a large and deep single vertical cuts
Beginning at the suprasternal notch at the base of the neck and ending at the top of the pubis
It's a skill that requires both great precision and intense concentration
Especially performed on someone with so much fat
So what I can feel at the moment is an awful
lot of yellow very Sort of greasy fatty tissue which
Is quite a thick layer in the body to size?
Reflecting the skin back from the ribcage here, and what that means is. I'm just kind of loosening it away with the muscle and
Give me a bit of room to Maneuver within the body
What we seem to have here is a breast implant. This is an incidental find sometimes when we do post mortems
It's not just about what we're expecting to find and it's incidental
there is a very large amount of fat here and
The reason it makes it so difficult is it actually is greasy it feels very much like butter
so what I'm doing here is just
trying to make sure that my
Knife doesn't slip too much on it
Mike did you want to come and take a look at it okay?
so
We can see immediately the thickness of fat that is here and even though there is a large amount on the anterior
chest wall the front of the chest
But there's also a very large amount around the abdomen the abdominal fat that is the most dangerous
Associated with the problems of obesity
It's quite a lot of fat around the organs
It's fatter in the amendment
It would appear that this lady is carrying much of her way in the abdominal fat and possibly around organs as well
So there's lots of changes which I think we'll get a better view of when we've opened the rest of the body
Everybody knows what obesity looks like from the outside
But unless you do a job like ours most people don't see what obesity looks like inside
I've done thousands of Post-Mortems
It's always a fascinating procedure even if it's a case where you've seen lots and lots of similar cases in the past
That particular case will be individual and you'll certainly learn from that
we'll never know exactly why our donor became so overweight the reasons for obesity are multi-layered and complicated a
mixture of lifestyle and environment
biology and psychology
But now that overweight is the new normal weight in the uk there is a whole new Young generation living with the consequences of obesity
I'm going to take my rib shears, and we use these specifically for this job as they can cut through bone and
What I'm going to do is just make some very
Even cuts right through all of these bones
you can hear the bones of snapping this lady isn't exactly young and
The older people get the more calcified their bones become so they become very very
crunchy Whereas younger people ten have much more
soft Bones
In order to do this job you have to be
stronger stomach to start with but I think that's just something you even know or don't and
I never would have considered doing this job. If I didn't know I had a strong stomach
I'm now removing the breast bone or the breast plate
sternum with
upward strokes, and this way I don't damage any of the
Pericardium which is the Sac that keeps the heart safe
The first time I saw somebody doing a post-mortem
I think I was just absolutely rapt I was fascinated and it's because the human body is an
Incredibly complex machine to open human being to see all of that
Absolutely perfect sort of Jigsaw of organs and perfectly in place. It really did make me feel very we
would
When you do an autopsy on somebody who's very slim the organs are there and they're very evidence?
It's like a game of of operate should all like one of those anatomical models that you would use at school
In a woman this size a lot of it is really hidden by this extra yellow bar
it is making it quite difficult to see the structures and much more difficult than it would if she was a
person
before color removes the heart and lungs
Mike want to take a look at the organs while they're still in the body
To see if we will discover any early indications of trauma or damage
You can see the heart here
There's a large amount of fat around the heart
There's more here than you would see normally quite considerably more
Underneath the heart and lungs in this area here is what you call the diaphragm
It's a big muscle that helps you breathe
Evenly and the diaphragm I was going to ask you very fatty for me right even even on the surface with a heart fat in
the diaphragm I'm eating there's more fat than usual and actually the thing you can see most is an
extremely, enlarged liver this is very very large and
It's got what we call fatty liver change, so this is a fatty liver and fatty liver is very much associated
with obesity
you can see there's a lot of fat around these organs, so
What would be between my hands now would be the kidneys now the kidneys always have fat around them
I think it's important while we're talking about the fat to realize that is a normal thing
Everybody has fat in however thin you are there will be some fat and fat
It's got very very important roles and one of those roles is to protect things is that too much fat
That is the problem
five is made up of cells called adipocytes which are fat cells and
Really for a long long time until very recently people thought that that was
Just an inert substance that just sort of sat bone didn't really do anything, but it's becoming increasingly
Understood now that that is actually a very active substance
Fat cells work almost like an Endocrine organ the people would have heard of some endocrine organs things like the thyroid gland which
Related to how much energy you have how cold you are?
And so forth the ovaries the testes so obviously these hormones
Related to the ovary in the testes define whether you're going to be a man or you're going to be a woman so those are
the Sorts of activities Hormones have so they're very very powerful things they become obvious that the adipocytes the fat cells duclair an
Endocrine type Role, and so have some very powerful effects that were previously unknown
The next stage of the Post-Mortem is the dissection of the heart and lungs
For might to be able to do this carla needs to remove the cardiorespiratory block from the body
I'm cutting through the diaphragm here just to make sure that I freeze the lungs completely
See them along Spine here
I'm going to do the exact same thing on the other side
And chop across the esophagus metric area here
And then all I need to do is basically pull the organs towards me at the same time as releasing these sort of white fibrous
Tissues that holding the organs for spine and then we'll get to a point
Where this blocks the cardiorespiratory block is completely free
Then we can take this out as one block
and we've got the heart and the lungs and the heart Sac the
pericardium
When you initially carry out post mortem?
and you hold an organs such as the heart in your hands and the heart is very symbolic and
You know using all sorts of logos. It's it has a sort of power and a sort of
agency that makes you kind of stop and think because it looks, so
Mundane, but then you realize that within it has the electrical impulses to keep a person alive
With the cardiorespiratory block removed from our donors body Mike can start his dissection of her lungs
Will we uncover any evidence of damage linked to her obesity?
I'm going to Detach the lungs
From the heart so we'll start off with the right lung
So just cutting through
Where the lung is attached, and that's the right lung detached to the left lung. I'm detaching
there
I'm just going to make some cuts across the lung just to see what the surface of the lung looks like these lungs actually look
quite healthy
There's no tumors or masses or anything like that in these lungs
But what there does seem to be and which should be evident now if I pick this lung up and squeeze it is
You can see the fluid dripping out of these lungs, and this is what we call pulmonary edema. That's
Essentially heart failure fluid this fluid is basically water. I know it looks red
That's because obviously it's within the body, and it's been mixed with blood. It isn't blood is much much thicker than that
This is really just a watery fluid and this is collected because this lady's got heart failure
this lady died from Heart failure from Hypertensive heart disease
But this lady is also obese she did not die from the obesity the obesity
increased the risk factors and
Was associated with the problems that led to her death?
Fluid has built up in this lady's lungs because her heart isn't working properly
She'd have probably been short of breath and had possibly had a cough
but also because the fluid sits in the chest when you lie flat
And that would have given her a sensation almost of drowning
When you become a doctor one of the questions that they teach you very early on is
How many pillows do you sleep with and that tends not to be because they're asking how comfortable you are at night?
It's because if somebody says oh, I can't sleep in a bed doctor
I have to sleep in a chair or I have to sleep with eight pillows sitting up that is very indicative of heart failure
And the startling discovery Mike has made in our donors lands
We now know that she would have felt the impacts of her obesity and heart failure every single day
Heart failure is not the same as a heart attack when a heart fails
It doesn't fail
immediately in this type of circumstance it fails over a long period of time, so the symptoms are gradual so
She met this lady may have been able to walk up ten flights of stairs three years ago
Then she suddenly found she got very breathless after five flights of stairs
Then she found that she was found it very very difficult to even walk up one flights of stairs or even carry her shopping it
Would have been a progressive disease as the heart became worse and worse and worse now the final event
Obviously when this lady's heart stopped working that would have been an Instantaneous event and led to her death
Now it's time for Mike to examine in detail the organ that catastrophic lee failed in our donor
What will we find out about how and why she might have died?
You can't really see the heart yet because the heart is sitting in a bag this is called the pericardial Sac
I'm just going to open that
and
so I can
Reflect that but and that's the heart there, so the heart now is in my hand
And you can see all the fat. I was talking to about earlier really isn't around the heart
It's really around the pericardium. There is a bit of fat around the heart which is here
This is absolutely typical in everybody's heart even a thin person's heart would have this and I'm going to cut off
the
pericardial Sac
This big blood vessel here is the Aorta this is the vessel that takes all the blood
From the heart around the body when I feel this heart it feels baggy a heart in someone who is very athletic
Their heart would be very tight very firm it would be like always picking up a piece of steak. This is more like a bad
What I'm going to do now is weigh this heart
So this heart is
449 grams that's a heavy Heart this lady is
Despite her weight this lady is actually quite a petite person. So you would expect her heart to be perhaps
275 grams something like that
So this is very much heavier than you would expect and that is the sort of sized heart you would expect
In someone who has got heart failure due to high blood pressure
which is what this lady suffered from
The heart basically has to pump to keep up the pressure the heart gets bigger and bigger and bigger
But there becomes a point where the heart can't get any bigger and it basically
exhausts itself
Now that he has discovered the shocking state of our donors heart might want to look at it from the inside
He cut some slices so he can examine the ventricles the walls of the heart that pump the blood
if you're 6 foot 8 all black
Second-row, or you're you know one of the professional footballers running around the pitch you need a lot of blood so the wall of the
left ventricle in a young fit person
It's usually an inch thick muscle all the way around now if you look at this lady
This lady's left ventricle is very very thin this is 8 millimeters something like that
That's because she developed high blood pressure to start off with the heart had spunk harder and harder in the end
What you get to is a state where the muscle can't keep the high blood pressure up and it starts to get thinner and thinner
And thinner and basically go from a thick muscular pump through to a paper bag that's not capable of pumping blood
Adequately around the body and we see a lot of these hearts. We see them on a background of hypertension
This is a common finding and becoming more common
Hypertension is high blood pressure obesity is well known to be one of the major risk factors for high blood pressure
So in this lady
they were not able to control that that led to
Changes within the heart which meant the heart failed it couldn't work properly, and that's what this lady died from
The next block of organs to be removed are the organs of the digestive system called the celiac block?
What I'm to do here is make sure that I've got the stomach and the lower bowel
liver and sleeve all together in one block for Mike to take a look at
And not damage the kidneys but at this point
I don't think I'm going to be able to damage them anyway because they also surrounded by such a large envelope of fat
So we've got some people mouth and we've got
Scott and bile and and then obviously a lot of blood the blood is mixed in with fat which is yellow
So that's giving us some orangie fluids
So multi-sensory rainbow at the moment every single thing that is in each of these blocks is incredibly important
and you know just amazing jobs for our body, and it's just a taste of
It's not very pleasant once they stopped working and they started to decompose a little bit
To completely free the organs
Carla needs to cut through the fibrous membrane that holds them to the spine at the back of the body
So this is a huge celiac block. It's incredibly heavy and the liver as you can see is taking up most of it
You can just see the spleen there and also the stomach and a bit of the small bowel as it hatched as well
When I first encountered a deceased person
I think what really struck me was just the stillness um and the cold
because of course I'd never that point felt flesh that was so cold and
It gave me a real sensation of kind of dipping my toe into very cold water
And then once I've done it that feeling had never quite left, and it was like if other
Subterranean World in
The next stage of the Post-mortem will we find any evidence of stack damage in the organs of our donors digestive system
this is the
Organs that include the liver the spleen
The stomach and the pancreas now this is much heavier than I would expect it to be in
A smaller individual largely because the liver is so big
First Mike is going to take a look at the organ that most people associate with obesity. This is the stomach
Basically just like a bag holds the food before the food goes through into the bow where it's actually
digested and there are actually many of
The treatments associated with obesity deal with the stomach and what they try to do is reduce the size of the stomach so that people
Have a feeling of being satisfied for meeting without eating so much
So there's a whole variety gastric bands fits around the stomach there's those I pass operations and so forth the stomach is
Very good at dilating
So if this lady had had a very large meal before she died and had not had opportunity to digest it
The stomach would be much more obvious, but this is a fairly typical
sized stomach
Next Mike will dissect the liver the organ he discovered showing such dramatic change when he saw it in the open body
But what would it reveal to us about the consequences of fats building up where it shouldn't?
First thing I saw when we opened the abdomen was the size of this liver and the fact that this liver showed marked fatty change
I'm going to make some slices through the liver just so I can see what the surface cut surface if the liver looks like
The sponge so I don't cut myself
So I've made some cuts across the liver there
And you can see that the surface of the liver is this sort of pinky color that's very characteristic
Of fatty liver change, it's very soft it almost feels like pate and consistency
Normal liver is quite soft, but not as soft as this in it
And it has a much meteor much redder bloody colour dark red the lightness in this is
caused by the fat within the liver and the fat is deposited within the hepatocyte which other liver cells and
this fat would obviously be pale in color and
liver cells themselves a dark, so the
Combination of the two gives uses light sort of pink color as much much lighter color than you'd expect a normal liver to be that
Is a classic sign of fatty liver disease, and it's becoming a major problem
And is one of the major reasons for liver transplant in the world the most common cause of fatty liver at the moment is
alcohol-related
Fatty liver, but we know that this lady drunk almost nothing
So it's very unlikely that this change is due to alcohol consumption
almost certainly an obesity related change
Fatty liver causes damage to the liver it can lead on to cirrhosis, and it can actually lead on to cancer as well
But even if people do not develop cancer or cirrhosis it can lead to liver failure
So there's a multiple ways that it can actually lead to the death of a patient it didn't lead to the death of this lady
Really because her heart was itself so bad, but this is very dramatic change within this liver
before the post mortem
We could never have known how dramatically damaged our donors liver would be or that should be carrying a second life threatening disease
But excess internal fat doesn't have to be a death sentence
The good news is the fight to beat the dangerous invisible fat can be won
It is a daily struggle
But the prize is big
Next Karla will remove the final group of organs, but even in the last stages of the postmortem. She takes nothing for granted
People who donate their bodies to medical science. We are giving a gift?
it's a gift that keeps on giving actually because as
A patient I think we all would prefer that our doctors and our surgeons have learned on
Something you know realistic to their job before they're let loose on other human limitations
You know you wouldn't really know a mechanic. Take care of your car
If you've never touched an engine, and it's very much the same thing with this
Wheel bodies are very unpredictable and very tale set compared to anything you don't fake anything like a virtual reality or a fake together
Because if you look here what you should be able to see are the kidneys
granted they always have a tiny capsule fat around them a bit like a sort of edamame being that you can pop out and
But these fatty capsules are very very large so all that you can really see at this point is a kind of yellow
glistening mess, really
So this is again indicative of the fact that she has an awful lot of extra fat around her organs
So I'm just slicing through the fibrous tissues and a bits of muscle that are keeping the kidneys
attached
to the spine and
It's really
Exactly the same thing that I've been doing with the rest of the organs and that is releasing them from the spine which is what?
Anchors them in Place and
Then I tend to deflect them all the way down and pull them out and this is the genitourinary block
And this is at least slightly smaller slightly easier to manage because we've only got the kidneys in this
How much fat you?
Might need to dissect the kidneys to find out just how much damage has been caused by all that excess fat
In the right kidney this is the left kidney
this in the middle is the big blood vessel that carries blood all the way down the body and
the most important and the first thing I can see is there's an
Unusual amount of fat around these kidneys now the kidneys always have fat around them kidneys are not
Protected by bone which means that they can be bashed and they can be here if you walk into something or something hits you
So this fat protects them this lady has much much more fat than I would expect
What I'm going to do first is just cut through
This fat which is called the peri renal fat
and
You can see quite clearly
How much fat there really is in a thin person?
This would probably be
Half of a third as thick as I can see here
This is bad news for this lady it means that she's more likely to have the complications of obesity
Because of the way she's carrying the fat this pale area here is the kidney. I'm just going to cut into the kidney
So the kidneys got a thick capsule around it
Now there's a small amount of fat in the middle of the kidney that's completely normal
That's where basically the kidney is responsible for filtering your blood and for making the urine that
Urine has to go somewhere
So your kidneys got a funnel
that collects all the urine from all the bits of the kidney takes it down through your ureter into the bladder and then when you
Want to go to the loo it goes out so this bit of fat sits around
That funnel area and is quite normal
I'm going to take the thick capsule off of the kidney surface to see what the surface of the kidney looks like
The surface of the Kidney ideally should be very very smooth
This kidney has got some scarring on the surface
There's areas of indentation
And pop marking there is clear damage to this kidney
Which would be associated with high blood pressure, and we know this lady had high blood pressure
Which is what led to her the changes within her heart and which led to her death
the visible scarring and pot marking we've discovered on our donors kidneys are the last of the revelation she will yield
Before Carla completes the Post-mortem and closes the body forever
One like finished his examination. I then begin the reconstruction and in a way that's one of the most important parts of the postmortem
What I do is I place all of the organs into a special
Viscera bag which will contain all of the elements that we've removed in the different blocks and I place that into the body cavity
And then I use very heavy
Post-Mortem twine to stitch as neatly as I can
Right along the incision. I made and we describe this as a baseball stitch. It does look very much like a zig zaggy stitch
Each Post-Mortem is unique and everything they reveal valuable
This donors gift was an opportunity for Mike and Carla to unveil the shocking truths hidden inside one body
irreversibly damaged by too much fat
the evisceration
occurred and it wasn't as easy to do as
It would be with a slightly smaller patient and it takes a lot more
Strength to cut through this this yellow adipose tissue which kind of blooms out of the abdomen and in this
you know practically neon yellow and and it looks very much like butter, and it has a greasy feel and
it
makes you suddenly very aware of
the fact in your own body well it made me me aware of that in my own body and
the effect of that might have on my organs the strain it might put on my heart and
The way it may affect my liver. I think they're doing a post-mortem and such as this is a really fantastic way for people to
Consider their own health and their own mortality
you
You never really know what we're going to find when we examine the patient the first thing
I noticed when the body had been opened was the markedly fatty liver
I know from the history that was provided that this lady died from heart failure, but the findings in her heart are
Extremely marked and the severity of them actually surprises me, but before we did the post-mortem
There was no indication that this lady had a fatty liver
And it's a possibility that even if this lady had not developed heart failure
She may have gone on to develop liver failure Due to the fatty change within the liver
We already knew a little about the way that this woman lived and how she died
What we couldn't have known before the post-mortem was the extent to which obesity would have ravaged her internal organs
from the suffocating fluid in her lungs
to her scarred kidneys
Creating a potent mix of life-threatening
obesity-related disease
the